Functionally Diverse Subsets in CD4 T Cell Responses Against Influenza
نویسندگان
چکیده
منابع مشابه
Clonal analysis of functionally distinct human CD4+ T cell subsets
A large number of CD4+ T cell clones, obtained from peripheral blood T lymphocytes by direct limiting dilution, allowed us to address the question whether functional heterogeneity exists within the human CD4+ T cell subset. Cytotoxic capacity of cloned T cells was analyzed with the use of anti-CD3 antibodies and target cells bearing FcR for murine IgG. 6 of 12 CD4+ clones obtained were able to ...
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The heterogeneity of CD4+ T cells has been investigated since the late 1970s, when their Th1 and Th2 subsets were coined. Later studies on the cutaneous form of the Leishmaniasis were focused on the experimental models of Leishmania major infection using the susceptible BALB/c and the resistant C57BL/6 mice. At the early 21st century, the regulatory T-cells subpopulation was introduced and its ...
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ژورنال
عنوان ژورنال: Journal of Clinical Immunology
سال: 2008
ISSN: 0271-9142,1573-2592
DOI: 10.1007/s10875-008-9266-4